{"id":365,"date":"2025-08-12T16:50:32","date_gmt":"2025-08-12T16:50:32","guid":{"rendered":"https:\/\/prado.mindconic.com\/?page_id=365"},"modified":"2025-08-21T13:35:10","modified_gmt":"2025-08-21T13:35:10","slug":"toxicology","status":"publish","type":"page","link":"https:\/\/pradopreclinical.com\/?page_id=365","title":{"rendered":"Toxicology"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"365\" class=\"elementor elementor-365\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1b7ac151 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"1b7ac151\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-45342dff e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"45342dff\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-27b40485 elementor-widget elementor-widget-elementskit-heading\" data-id=\"27b40485\" data-element_type=\"widget\" data-widget_type=\"elementskit-heading.default\">\n\t\t\t\t\t<div class=\"ekit-wid-con\" ><div class=\"ekit-heading elementskit-section-title-wraper text_center   ekit_heading_tablet-   ekit_heading_mobile-\"><h2 class=\"ekit-heading--title elementskit-section-title \">Toxicology<\/h2>\t\t\t\t<div class='ekit-heading__description'>\n\t\t\t\t\t<p>We offer a full range of GLP-compliant toxicology studies to assess the safety of pharmaceuticals, chemicals, and medical devices.<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-44630fd2 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"44630fd2\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3471932f e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"3471932f\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a586fe4 e-n-tabs-mobile elementor-widget elementor-widget-n-tabs\" data-id=\"a586fe4\" data-element_type=\"widget\" data-widget_type=\"nested-tabs.default\">\n\t\t\t\t\t\t\t<div class=\"e-n-tabs\" data-widget-number=\"173567972\" aria-label=\"Tabs. Open items with Enter or Space, close with Escape and navigate using the Arrow keys.\">\n\t\t\t<div class=\"e-n-tabs-heading\" role=\"tablist\">\n\t\t\t\t\t<button id=\"e-n-tab-title-1735679721\" class=\"e-n-tab-title\" aria-selected=\"true\" data-tab-index=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"e-n-tab-content-1735679721\" style=\"--n-tabs-title-order: 1;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tSingle and Repeat Dose Toxicity\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1735679722\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1735679722\" style=\"--n-tabs-title-order: 2;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tIrritation &amp; Sensitization Tests\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1735679723\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1735679723\" style=\"--n-tabs-title-order: 3;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tGenetic Toxicity (Genotoxicity)\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1735679724\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1735679724\" style=\"--n-tabs-title-order: 4;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tReproductive &amp; Developmental Toxicity\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t<button id=\"e-n-tab-title-1735679725\" class=\"e-n-tab-title\" aria-selected=\"false\" data-tab-index=\"5\" role=\"tab\" tabindex=\"-1\" aria-controls=\"e-n-tab-content-1735679725\" style=\"--n-tabs-title-order: 5;\">\n\t\t\t\t\t\t<span class=\"e-n-tab-title-text\">\n\t\t\t\tInhalation Toxicity\t\t\t<\/span>\n\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t\t\t<div class=\"e-n-tabs-content\">\n\t\t\t\t<div id=\"e-n-tab-content-1735679721\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1735679721\" data-tab-index=\"1\" style=\"--n-tabs-title-order: 1;\" class=\"e-active elementor-element elementor-element-a20693b e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"a20693b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-01daa87 elementor-widget elementor-widget-heading\" data-id=\"01daa87\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Single and Repeat Dose Toxicity<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8be85d5 elementor-widget elementor-widget-text-editor\" data-id=\"8be85d5\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0Evaluating the short-term and long-term harmful effects of substances on living organisms. This includes single-dose studies in rodents, as well as repeat-dose studies conducted over periods like 7-14 days, 28 days, 90 days, and extended chronic studies up to 180 days. We also conduct repeat-dose inhalation studies.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c653137 elementor-widget elementor-widget-image\" data-id=\"c653137\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"500\" src=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg\" class=\"attachment-large size-large wp-image-471\" alt=\"\" srcset=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg 600w, https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology-300x250.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1735679722\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1735679722\" data-tab-index=\"2\" style=\"--n-tabs-title-order: 2;\" class=\" elementor-element elementor-element-5b1fe8b e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"5b1fe8b\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f4335de elementor-widget elementor-widget-heading\" data-id=\"f4335de\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Irritation &amp; Sensitization Tests<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e6ae2e3 elementor-widget elementor-widget-text-editor\" data-id=\"e6ae2e3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0Assessing potential skin and eye irritation, and identifying substances that might cause allergic reactions (skin sensitization) through methods like the Guinea Pig Maximization Test (GPMT) and Buehler Test.<\/p><p>\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3732e4c elementor-widget elementor-widget-image\" data-id=\"3732e4c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"500\" src=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg\" class=\"attachment-large size-large wp-image-471\" alt=\"\" srcset=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg 600w, https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology-300x250.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1735679723\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1735679723\" data-tab-index=\"3\" style=\"--n-tabs-title-order: 3;\" class=\" elementor-element elementor-element-04a2d9f e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"04a2d9f\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3d68d8d elementor-widget elementor-widget-heading\" data-id=\"3d68d8d\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Genetic Toxicity (Genotoxicity)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d2c501 elementor-widget elementor-widget-text-editor\" data-id=\"3d2c501\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>\u00a0Investigating whether a substance can cause damage to genetic material (DNA, Gene, Chromosomes). This includes various in vitro (cell-based) and in vivo (animal-based) assays such as the Ames Assay (Reverse Mutation), Micronucleus Test (MNT), Chromosomal Aberration Assay, and In vitro Mammalian Gene Mutation Assay.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6667801 elementor-widget elementor-widget-image\" data-id=\"6667801\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"500\" src=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg\" class=\"attachment-large size-large wp-image-471\" alt=\"\" srcset=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg 600w, https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology-300x250.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1735679724\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1735679724\" data-tab-index=\"4\" style=\"--n-tabs-title-order: 4;\" class=\" elementor-element elementor-element-0930600 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"0930600\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-868c73e elementor-widget elementor-widget-heading\" data-id=\"868c73e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Reproductive &amp; Developmental Toxicity<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1734c8a elementor-widget elementor-widget-text-editor\" data-id=\"1734c8a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Studying the potential adverse effects of substances on fertility, pregnancy, and the development of offspring. This encompasses and assessments of male and female fertility, embryo-foetal development studies in rodents and rabbits, and Extended One Generation Reproductive Toxicity (EOGRT).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a46b6ab elementor-widget elementor-widget-image\" data-id=\"a46b6ab\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"500\" src=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg\" class=\"attachment-large size-large wp-image-471\" alt=\"\" srcset=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg 600w, https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology-300x250.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div id=\"e-n-tab-content-1735679725\" role=\"tabpanel\" aria-labelledby=\"e-n-tab-title-1735679725\" data-tab-index=\"5\" style=\"--n-tabs-title-order: 5;\" class=\" elementor-element elementor-element-4cb05d3 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-child\" data-id=\"4cb05d3\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bb78371 elementor-widget elementor-widget-heading\" data-id=\"bb78371\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Inhalation Toxicity<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5119701 elementor-widget elementor-widget-text-editor\" data-id=\"5119701\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Evaluating the harmful effects of substances when inhaled in a single or repeatedexposure.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a496875 elementor-widget elementor-widget-image\" data-id=\"a496875\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"500\" src=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg\" class=\"attachment-large size-large wp-image-471\" alt=\"\" srcset=\"https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology.jpg 600w, https:\/\/pradopreclinical.com\/wp-content\/uploads\/2025\/08\/toxicology-300x250.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6ba2bcc e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no e-con e-parent\" data-id=\"6ba2bcc\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Toxicology We offer a full range of GLP-compliant toxicology studies to assess the safety of pharmaceuticals, chemicals, and medical devices. Single and Repeat Dose Toxicity Irritation &amp; Sensitization Tests Genetic Toxicity (Genotoxicity) Reproductive &amp; Developmental Toxicity Inhalation Toxicity Single and Repeat Dose Toxicity \u00a0Evaluating the short-term and long-term harmful effects of substances on living organisms. This includes single-dose studies in rodents, as well as repeat-dose studies conducted over periods like 7-14 days, 28 days, 90 days, and extended chronic studies up to 180 days. We also conduct repeat-dose inhalation studies. Irritation &amp; Sensitization Tests \u00a0Assessing potential skin and eye irritation, and identifying substances that might cause allergic reactions (skin sensitization) through methods like the Guinea Pig Maximization Test (GPMT) and Buehler Test. \u00a0 Genetic Toxicity (Genotoxicity) \u00a0Investigating whether a substance can cause damage to genetic material (DNA, Gene, Chromosomes). This includes various in vitro (cell-based) and in vivo (animal-based) assays such as the Ames Assay (Reverse Mutation), Micronucleus Test (MNT), Chromosomal Aberration Assay, and In vitro Mammalian Gene Mutation Assay. Reproductive &amp; Developmental Toxicity Studying the potential adverse effects of substances on fertility, pregnancy, and the development of offspring. This encompasses and assessments of male and female fertility, embryo-foetal development studies in rodents and rabbits, and Extended One Generation Reproductive Toxicity (EOGRT). Inhalation Toxicity Evaluating the harmful effects of substances when inhaled in a single or repeatedexposure. Single and Repeat Dose Toxicity \u00a0Evaluating the short-term and long-term harmful effects of substances on living organisms. This includes single-dose studies in rodents, as well as repeat-dose studies conducted over periods like 7-14 days, 28 days, 90 days, and extended chronic studies up to 180 days. We also conduct repeat-dose inhalation studies. Irritation &amp; Sensitization Tests \u00a0Assessing potential skin and eye irritation, and identifying substances that might cause allergic reactions (skin sensitization) through methods like the Guinea Pig Maximization Test (GPMT) and Buehler Test. \u00a0 Genetic Toxicity (Genotoxicity) \u00a0Investigating whether a substance can cause damage to genetic material (DNA, Gene, Chromosomes). This includes various in vitro (cell-based) and in vivo (animal-based) assays such as the Ames Assay (Reverse Mutation), Micronucleus Test (MNT), Chromosomal Aberration Assay, and In vitro Mammalian Gene Mutation Assay. Reproductive &amp; Developmental Toxicity Studying the potential adverse effects of substances on fertility, pregnancy, and the development of offspring. This encompasses and assessments of male and female fertility, embryo-foetal development studies in rodents and rabbits, and Extended One Generation Reproductive Toxicity (EOGRT). Inhalation Toxicity Evaluating the harmful effects of substances when inhaled in a single or repeatedexposure.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-365","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=\/wp\/v2\/pages\/365","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=365"}],"version-history":[{"count":31,"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=\/wp\/v2\/pages\/365\/revisions"}],"predecessor-version":[{"id":615,"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=\/wp\/v2\/pages\/365\/revisions\/615"}],"wp:attachment":[{"href":"https:\/\/pradopreclinical.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}